c(phg-isoDGR-(NMe)k) |
| カタログ番号GC65455 |
c(phg-isoDGR-(NMe)k) は選択的で強力な α5β1-インテグリン リガンドで、IC50 は 2.9 nM です。
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Cas No.: 1844830-65-4
Sample solution is provided at 25 µL, 10mM.
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c(phg-isoDGR-(NMe)k) is a selective and potent α5β1-integrin ligand with an IC50 of 2.9 nM[1].
c(phg-isoDGR-(NMe)k) is trimerized with the chelator TRAP and used as a positron-emission tomography tracer for monitoring α5β1 integrin expression in a M21 mouse xenograft[1].
[1]. Kapp TG, et al. N-Methylation of isoDGR Peptides: Discovery of a Selective α5β1-Integrin Ligand as a Potent Tumor Imaging Agent. J Med Chem. 2018 Mar 22;61(6):2490-2499.
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