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Atrial Natriuretic Peptide (1-28) (rat) (trifluoroacetate salt) (Synonyms: ANF, ANP, Atrial Natriuretic Factor, α-Atriopeptin (rat))

カタログ番号GC42871

心臓の心筋細胞によって分泌される、プレプロ-ANPのプロテオリシスによって生成された内因性ペプチドである心房性ナトリウム利尿ペプチド(ANP)です。

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Atrial Natriuretic Peptide (1-28) (rat) (trifluoroacetate salt) 化学構造

サイズ 価格 在庫数 個数
250μg
$165.00
在庫あり
500μg
$296.00
在庫あり
1mg
$494.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

心臓の心筋細胞によって分泌される、プレプロ-ANPのプロテオリシスによって生成された内因性ペプチドである心房性ナトリウム利尿ペプチド(ANP)は、血管収縮を減少させ、レニン分泌を抑制し、ナトリウム排泄を増加させる腎臓および循環系に影響を与えます。ラット腎皮質外来では、外因性ラットANPは量依存的に基礎的なレニン放出を抑制し、IC50値が58 nMでイソプロテレノール誘発性のレニン放出も抑制します。 ANP(8μg / kg)は麻酔下のラットでは血漿中のレニン活性とcAMP濃度を低下させてcGMP濃度を増加させます。また、150 ngの投与量で脳室内投与した場合に自然発生高血圧およびコントロールラットで平均動脈血圧上昇効果誘発素アルギニンバソプレッシンに対する阻害作用があります。 ANP(1-28)(rat)は、ラットタンパク質配列に対応する28アミノ酸ペプチドです。

Chemical Properties

Cas No. SDF
同義語 ANF, ANP, Atrial Natriuretic Factor, α-Atriopeptin (rat)
Formula C128H205N45O39S2•XCF3COOH M.Wt 3062.4
溶解度 Water: 1 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 0.3265 mL 1.6327 mL 3.2654 mL
5 mM 0.0653 mL 0.3265 mL 0.6531 mL
10 mM 0.0327 mL 0.1633 mL 0.3265 mL
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Average Rating: 5 ★★★★★ (Based on Reviews and 28 reference(s) in Google Scholar.)

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