D-α-Hydroxyglutaric Acid |
| カタログ番号: GC18583 |
D-α-ヒドロキシグルタル酸 ((R)-2-ヒドロキシグルタル酸) は、神経代謝疾患 D-2-ヒドロキシグルタル酸尿症で蓄積する主要な代謝産物です。
Sample solution is provided at 25 µL, 10mM.
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| Cas No. | 13095-47-1 | SDF | |
| Chemical Name | 2R-hydroxy-pentanedioic acid | ||
| Canonical SMILES | OC([C@@H](CCC(O)=O)O)=O | ||
| Formula | C5H8O5 | M.Wt | 148.1 |
| 溶解度 | 75mg/mL in Water (Need ultrasonic); Insoluble in DMSO | Storage | Store at -20°C |
| 一般的なヒント | より高い溶解度を得るためには、37 度でチューブを温めてください。それを超音波風呂で揺らして泡立てます。在庫ソリューションは -20度以下で数カ月保存できます。 | ||
| 出荷条件 | 評価サンプルソリューション: zip with blue ice その他すべての利用可能サイズ: ship with RT, or blue ice |
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Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
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