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DL-threo-Isocitric Acid (sodium salt hydrate)

カタログ番号GC47245

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DL-threo-Isocitric Acid (sodium salt hydrate) 化学構造

Cas No.: N/A

サイズ 価格 在庫数 個数
500 mg
$60.00
在庫あり
1 g
$108.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description of DL-threo-Isocitric Acid (sodium salt hydrate)

DL-threo-Isocitric acid is a racemic mixture of D-threo-isocitric acid and L-threo-isocitric acid. It has been used as a substrate to measure the activity of yeast isocitrate lyase in C. albicans, S. cerevisiae, or K. lactis cell-free extracts.1,2

1.Koivistoinen, O.M., Kuivanen, J., Barth, D., et al.Glycolic acid production in the engineered yeasts Saccharomyces cerevisiae and Kluyveromyces lactisMicrob. Cell Fact.1282(2013) 2.Ansari, M.A., Fatima, Z., Ahmad, K., et al.Monoterpenoid perillyl alcohol impairs metabolic flexibility of Candida albicans by inhibiting glyoxylate cycleBiochem. Biophys. Res. Commun.495(1)560-566(2018)

Chemical Properties of DL-threo-Isocitric Acid (sodium salt hydrate)

Cas No. N/A SDF
Canonical SMILES [O-]C(C[C@@H](C([O-])=O)[C@H](O)C([O-])=O)=O.[Na+].[Na+].[Na+].O
Formula C6H5O7.3Na [XH2O] M.Wt 258.1
溶解度 PBS (pH 7.2): 5mg/mL Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of DL-threo-Isocitric Acid (sodium salt hydrate)

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.8745 mL 19.3723 mL 38.7447 mL
5 mM 0.7749 mL 3.8745 mL 7.7489 mL
10 mM 0.3874 mL 1.9372 mL 3.8745 mL
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**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

計算

In vivo Formulation Calculator (Clear solution) of DL-threo-Isocitric Acid (sodium salt hydrate)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 23 reference(s) in Google Scholar.)

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