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(E)-2-Decenoic acid (Synonyms: trans-2-Decylenic Acid)

カタログ番号GC15373

ローヤルゼリーに含まれる不飽和脂肪酸

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(E)-2-Decenoic acid 化学構造

Cas No.: 334-49-6

サイズ 価格 在庫数 個数
10mM (in 1mL DMSO)
$38.00
在庫あり
25mg
$39.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(E)-2-デセノ酸は、蜂の王乳分泌物から単離された興味深い脂肪酸です。

(E)-2-デセノ酸は、ローヤルゼリーに固有の脂肪酸である10-ヒドロキシトランス-2-デセノ酸と共に単離されます。 (E)-2-Decenoic acid および 10-hydroxy-trans-2-decenoic acid は、両方ともエストロゲン作用を示すために記述されており、これらの脂肪酸はエストラジオール受容体βへの17β-エストラジオール結合の阻害を示します。

References:
[1]. Naumowicz M, Petelska AD, Figaszewski ZA.Impedance analysis of complex formation equilibria in phosphatidylcholine bilayers containing decanoic acid or decylamine.Cell Biochem Biophys. 2011 Sep;61(1):145-55.
[2]. Kumar A, Singh S, Jain S, Kumar P.Synthesis, antimicrobial evaluation, QSAR and in Silico ADMET studies of decanoic acid derivatives.Acta Pol Pharm. 2011 Mar-Apr;68(2):191-204.
[3]. Petelska AD, Figaszewski ZA.Interfacial tension of the lipid membrane formed from phosphatidylcholine-decanoic acid and phosphatidylcholine-decylamine systems.J Membr Biol. 2011 May;241(2):103-8.
[4]. Hattori N et al.Royal jelly and its unique fatty acid, 10-hydroxy-trans-2-decenoic acid, promote neurogenesis by neural stem/progenitor cells in vitro. Biomed Res. 2007 Oct;28(5):261-6.
[5]. Suzuki KM et al. Estrogenic activities of Fatty acids and a sterol isolated from royal jelly. Evid Based Complement Alternat Med. 2008 Sep;5(3):295-302.

Chemical Properties

Cas No. 334-49-6 SDF
同義語 trans-2-Decylenic Acid
Chemical Name (E)-dec-2-enoic acid
Canonical SMILES CCCCCCCC=CC(=O)O
Formula C10H18O2 M.Wt 170.25
溶解度 ≥ 8.8 mg/mL in DMSO, ≥ 161.4 mg/mL in EtOH Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 5.8737 mL 29.3686 mL 58.7372 mL
5 mM 1.1747 mL 5.8737 mL 11.7474 mL
10 mM 0.5874 mL 2.9369 mL 5.8737 mL
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計算

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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