(E/Z)-GSK-3β inhibitor 1 |
| カタログ番号GC62736 |
(E/Z)-GSK-3β阻害剤１は、（Ｅ）－ＧＳＫ－３８８８８８８９９９９９９９４６のラセミ化合物である。阻害剤1および(Z)-GSK-3βインヒビター1異性体。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 3367-88-2
Sample solution is provided at 25 µL, 10mM.
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(E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].
[1]. Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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