Eicosapentaenoic Acid ethyl ester-d5 (Synonyms: EPA ethyl ester-d5) |
| カタログ番号GC47281 |
多様な生物学的活性を持つ神経ペプチド
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Fish oils in the diet have anti-
1.von Schacky, C.A review of omega-3 ethyl esters for cardiovascular prevention and treatment of increased blood triglyceride levelsVascular Health and Risk Management2(3)251-262(2006) 2.Wada, M., DeLong, C.J., Hong, Y.H., et al.Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and productsJ. Biol. Chem.282(31)22254-22266(2007) 3.Hong, D.D., Takahashi, Y., Kushiro, M., et al.Divergent effects of eicosapentaenoic and docosahexaenoic acid ethyl esters, and fish oil on hepatic fatty acid oxidation in the ratBiochimica et Biophysica Acta163529-36(2003) 4.Arachchige, P.G., Takahashi, Y., and Ide, T.Dietary sesamin and docosahexaenoic and eicosapentaenoic acids synergistically increase the gene expression of enzymes involved in hepatic peroxisomal fatty acid oxidation in ratsMetabolism: Clinical and Experimental55381-390(2006) 5.PÉrez-Echarri, N., PÉrez-Matute, P., Marcos-GÓmez, B., et al.Down-regulation in muscle and liver lipogenic genes: EPA ethyl ester treatment in lean and overweight (high-fat-fed) ratsJournal of Nutritional Biochemistry(2008) 6.PÉrez-Matute, P., PÉrez-Echarri, N., MartÍnez, J.A., et al.Eicosapentaenoic acid actions on adiposity and insulin resistance in control and high-fat-fed rats: Role of apoptosis, adiponectin and tumor necrosis factor-αBritish Journal of Nutrition97389-398(2007)
| Cas No. | N/A | SDF | |
| 同義語 | EPA ethyl ester-d5 | ||
| Canonical SMILES | CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(OC([2H])([2H])C([2H])([2H])[2H])=O | ||
| Formula | C22H29D5O2 | M.Wt | 335.5 |
| 溶解度 | DMF: >100 mg/ml,DMSO: >100 mg/ml,Ethanol: >100 mg/ml | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.9806 mL | 14.9031 mL | 29.8063 mL |
| 5 mM | 0.5961 mL | 2.9806 mL | 5.9613 mL |
| 10 mM | 0.2981 mL | 1.4903 mL | 2.9806 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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