(7-Diethylaminocoumarin-3-yl)carbonyl-Amyloid β-Protein (1-40) |
カタログ番号GA20024 |
フルオレセント染料(7-ジエチルアミノクマリン-3-イル)カルボニル(DACまたはDEAC)でN末端修飾されたアミロイドβタンパク質(1-40)。この誘導体は、元のペプチドと非常に似た振る舞いをするため、さまざまな膜に対するアミロイドβタンパク質(1-40)の結合特性を評価するために利用できます。水溶液中では蛍光色素はほとんど蛍光しないが、膜への結合により蛍光強度が増加します(λex = 430 nm、λem = 470 nm)。リピッド二重層内のGM1ガングリオシドおよびコレステロール含有量の増加は、このペプチドの結合を促進しました。リン酸コリンおよびリン酸セリンでは親和性は観察されませんでした。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1802087-66-6
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
フルオレセント染料(7-ジエチルアミノクマリン-3-イル)カルボニル(DACまたはDEAC)でN末端修飾されたアミロイドβタンパク質(1-40)。この誘導体は、さまざまな膜に対するアミロイドβタンパク質(1-40)の結合特性を評価するために利用できます。
Cas No. | 1802087-66-6 | SDF | |
Formula | C208H308N54O61S | M.Wt | 4573.13 |
溶解度 | Soluble in DMSO | Storage | Store at -20°C |
General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. |
Prepare stock solution | |||
1 mg | 5 mg | 10 mg | |
1 mM | 0.2187 mL | 1.0933 mL | 2.1867 mL |
5 mM | 0.0437 mL | 0.2187 mL | 0.4373 mL |
10 mM | 0.0219 mL | 0.1093 mL | 0.2187 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Average Rating: 5
(Based on Reviews and 38 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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