(Nle³⁵)-Amyloid β-Protein (1-42) |
カタログ番号GA20260 |
Met³のチオエーテルは、Aβ1-42によって誘発される酸化ストレスとその神経毒性に重要な役割を果たします。ノールロイシンアナログのAβ1-42 M35Nleは、神経毒性が欠けているものの、形態学的には元の配列と区別できないフィブリルを形成します。
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Cas No.: 1802086-51-6
Sample solution is provided at 25 µL, 10mM.
The thioether of Met³ plays a critical role in the oxidative stress induced by Aβ 1-42 and its neurotoxicity. The norleucine analog Aβ 1-42 M35Nle forms fibrils morphologically indistinguishable from the ones of the native sequence thoug
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