2,2,5,7,8-Pentamethyl-6-Chromanol |
| カタログ番号GC35069 |
2,2,5,7,8-ペンタメチル-6-クロマノール (PMC) は、ビタミン E (α-トコフェロール) の抗酸化部分です。 2,2,5,7,8-ペンタメチル-6-クロマノールは、強力なアンドロゲン受容体 (AR) シグナル伝達調節と前立腺癌細胞株に対する抗癌活性を持っています。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 950-99-2
Sample solution is provided at 25 µL, 10mM.
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2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines[1].
[1]. Kyriakopoulos CE, et al. A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer. Invest New Drugs. 2016 Apr;34(2):225-30.
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