CMD178 TFA |
| カタログ番号GC35715 |
CMD178 TFA は、IL-2/s IL-2Rα シグナル伝達によって誘導される Foxp3 および STAT5 の発現を一貫して低下させ、Treg 細胞の発生を阻害するリードペプチドです。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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CMD178 (TFA) is a lead peptide that consistently reduces the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling. CMD178 (TFA) also is an inhibitor of STAT5 and inhibits Tregcells development[1].
[1]. Price-Troska T, et al. Inhibiting IL-2 signaling and the regulatory T-cell pathway using computationally designed peptides. Invest New Drugs. 2018 Apr 26.
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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