Complement C5-IN-1 |
| カタログ番号GC35724 |
補体Ｃ５－ＩＮ－１（化合物７）は、補体成分５タンパク質（Ｃ５）の小分子阻害剤である。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2365402-67-9
Sample solution is provided at 25 µL, 10mM.
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Complement C5-IN-1 (Compound 7) is a small-molecule inhibitor of complement component 5 protein (C5). Complement C5-IN-1 interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) deposition in 50% human whole blood with an IC50 of 0.77 µM[1].
[1]. Jendza K, et al. A small-molecule inhibitor of C5 complement protein. Nat Chem Biol. 2019 Jul;15(7):666-668.
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