MF-438 |
| カタログ番号GC36604 |
MF-438 は、rSCD1 の IC50 が 2.3 nM である強力な経口投与可能なステアロイル CoA デサチュラーゼ 1 (SCD1) 阻害剤です 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 921605-87-0
Sample solution is provided at 25 µL, 10mM.
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MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1[1]. EC50: 2.3 nM (rSCD1)[1]
MF-438 exhibits an ED50 between 1 and 3 mg/kg in a mouse model[1].
[1]. LÉger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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