(-)-α-Pinene (Synonyms: NSC 7727) |
| カタログ番号GC38677 |
(-)-α-ピネンはモノテルペンであり、GABAA-ベンゾジアゼピン (BZD) 受容体に直接結合し、BZD 結合部位で部分モジュレーターとして作用することにより、睡眠改善特性を示します。
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Cas No.: 7785-26-4
Sample solution is provided at 25 µL, 10mM.
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(-)-α-Pinene is a monoterpene and shows sleep enhancing property through a direct binding to GABAA-benzodiazepine (BZD) receptors by acting as a partial modulator at the BZD binding site[1].
(-)-α-pinene enhances the quantity of non-rapid eye movement sleep (NREMS) without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission, acting as a partial modulator of GABAA-BZD receptors and directly binding to the BZD binding site of GABAA receptor[1].
[1]. Yang H, et al. α-Pinene, a Major Constituent of Pine Tree Oils, Enhances Non-Rapid Eye Movement Sleep in Micethrough GABAA-benzodiazepine Receptors.
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