α-Linolenic Acid-d5 MaxSpec• Standard (Synonyms: ALA-d5, C18:3 (9Z,12Z,15Z)-d5, C18:3 n-3-d5) |
カタログ番号GC45602 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 145191-04-4
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
α-リノレン酸-d5(ALA-d5)は、植物に存在する必須のω-3多価不飽和脂肪酸であるα-リノレン酸をGC-またはLC-MSによって定量するための内部標準として使用されます。1生体内では、より長い鎖状脂肪酸であるエイコサペンタエン酸、ドコサペンタエン酸、ドコサヘキサエン酸に変換されます。2また、脂肪酸β-oxidationを介してエネルギー源や飽和および一価不飽和脂肪酸の合成に分解されたり、脂肪組織に貯留されたりします。ALAを含む食品の摂取は心血管疾患のリスクがわずかに低下することが報告されています。1 ALA-d5 MaxSpec • 標準は質量分析法および関連アプリケーションで定量的再現性が必要な場合に特別に調製されたALA-d5 の定量グレード標準です。この溶液は重量法で調製されており、アルゴンで封印された非活性化ガラスアンプルに供給されます。濃度は独立して調製されたキャリブレーション標準と比較して確認されました。このALA-d5 MaxSpec • 標準は同一性、純度、安定性、および濃度仕様を満たすことが保証されており、バッチ固有の分析証明書が付属します。製品の保存や取扱い条件に従って品質を維持するために推奨事項に従ってください。なお、フィアルに添加する溶液量は記載量を超過していますので、キャリブレーション基準の調製時に正確な体積測定が必要です。
References
1. Pan, A., Chen, M., Chowdhury, R., et al. α-Linolenic acid and risk of cardiovascular disease: A systematic review and meta-analysis. Am. J. Clin. Nutr. 96(6), 1262-1273 (2012).
2. Burdge, G.C. Metabolism of α-linolenic acid in humans. Prostaglandins Leukot. Essent. Fatty Acids 75(3), 161-168 (2006).
Cas No. | 145191-04-4 | SDF | |
同義語 | ALA-d5, C18:3 (9Z,12Z,15Z)-d5, C18:3 n-3-d5 | ||
Canonical SMILES | [2H]C([2H])([2H])C([2H])([2H])/C=C\C/C=C\C/C=C\CCCCCCCC(O)=O | ||
Formula | C18H25D5O2 | M.Wt | 283.5 |
溶解度 | Soluble in DMSO | Storage | Store at -20°C |
General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. |
Prepare stock solution | |||
1 mg | 5 mg | 10 mg | |
1 mM | 3.5273 mL | 17.6367 mL | 35.2734 mL |
5 mM | 0.7055 mL | 3.5273 mL | 7.0547 mL |
10 mM | 0.3527 mL | 1.7637 mL | 3.5273 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Average Rating: 5
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