GDC-6036 |
| カタログ番号GC64510 |
ＧＤＣ－６０３６（化合物１７ａ）は、ＩＣ５０が<０．０１μＭの強力なＫ－Ｒａｓ Ｇ１２Ｃ阻害剤である。 GDC-6036 は、K-Ras G12C-アルキル化 HCC1171 細胞で 2 nM の EC50 を持っています。
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Cas No.: 2417987-45-0
Sample solution is provided at 25 µL, 10mM.
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GDC-6036 (compound 17a) is a potent K-Ras G12C inhibitor with an IC50 of <0.01 μM. GDC-6036 has an EC50 of 2 nM in K-Ras G12C-alkylation HCC1171 cells[1].
[1]. Sushant Malhotra, et al. Fused ring compounds. WO2020097537A2.
Review for GDC-6036
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for GDC-6036
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