IRAK4-IN-6 |
カタログ番号GC61944 |
IRAK4-IN-6 は、IC50 が 4 nM の経口有効かつ選択的な IRAK4 阻害剤であり、MyD88 L265P 変異型びまん性大細胞型 B 細胞リンパ腫を標的としています。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2454244-02-9
Sample solution is provided at 25 µL, 10mM.
IRAK4-IN-6 is an orally efficacious and selective IRAK4 inhibitor with an IC50 of 4 nM, and targetes MyD88 L265P mutant diffuse large B cell lymphoma[1].
References:
[1]. Degorce SL, et al. Discovery of a Series of 5-Azaquinazolines as Orally Efficacious IRAK4 Inhibitors TargetingMyD88L265P Mutant Diffuse Large B Cell Lymphoma. J Med Chem. 2019 Nov 1.
Average Rating: 5
(Based on Reviews and 19 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *