JNJ DGAT2-A |
| カタログ番号GC50285 |
JNJ DGAT2-A は、選択的ジアシルグリセロール アシルトランスフェラーゼ 2 (DGAT2) 阻害剤であり、ヒト DGAT2 発現 Sf9 昆虫細胞膜における IC50 値は 0.14 μM です。
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Cas No.: 1962931-71-0
Sample solution is provided at 25 µL, 10mM.
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DGAT2 inhibitor (IC50 = 140 nM). Exhibits >70-fold selectivity for DGAT2 over DGAT1 and MGAT2.
Qi et al (2012) The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2 J.Lipid Res. 53 1106 PMID:22493088 |Irshad et al (2017) Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes. J.Lipid Res. 58 15 PMID:27836993
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