Laurdan |
| カタログ番号GC18338 |
Laurdanは、細胞膜に結合した際に、細胞膜のリン脂質相に対するスペクトル感度を示す膜透過性の蛍光プローブです。
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Cas No.: 74515-25-6
Sample solution is provided at 25 µL, 10mM.
Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound.[1] Quantitation of generalized polarization (GP) of laurdan can be used to identify phospholipid phase. When excited at 340 nm, GP values are 0.6 and -0.2 for gel phase and liquid crystalline phase, respectively. GP does not change with polar head group or pH (in the range 4-10); it changes only with phase state.
Reference:
[1]. Parasassi, T., De Stasio, G., Ravagnan, G., et al. Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence. Biophys. J. 60(1), 179-189 (1991).
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