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N-acetyl-L-Carnosine (Synonyms: NAC)

カタログ番号GC41368

天然のヒスチジン含有ジペプチドである N-アセチル-L-カルノシンは、薬理学的主要な L-カルノシンの供給源です。

Products are for research use only. Not for human use. We do not sell to patients.

N-acetyl-L-Carnosine 化学構造

Cas No.: 56353-15-2

サイズ 価格 在庫数 個数
10mM (in 1mL Water)
$22.00
在庫あり
100mg
$20.00
在庫あり
500mg
$41.00
在庫あり
1g
$60.00
在庫あり
5g
$154.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description of N-acetyl-L-Carnosine

N-acetyl-L-Carnosine (NAC) is a natural imidazole-containing dipeptide that has antioxidant activities in cells, particularly against lipid peroxidation. Formulations containing NAC may prevent or resolve cataracts when added to the eyes of animals, presumably through the conversion of NAC to another antioxidant, carnosine. NAC and related dipeptides, delivered in specific formulations, may also have protective effects for skin.

Chemical Properties of N-acetyl-L-Carnosine

Cas No. 56353-15-2 SDF
同義語 NAC
Canonical SMILES OC([C@@H](NC(CCNC(C)=O)=O)CC1=CN=CN1)=O
Formula C11H16N4O4 M.Wt 268.3
溶解度 DMSO: 0.5 mg/ml,PBS (pH 7.2): 10 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of N-acetyl-L-Carnosine

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.7272 mL 18.6359 mL 37.2717 mL
5 mM 0.7454 mL 3.7272 mL 7.4543 mL
10 mM 0.3727 mL 1.8636 mL 3.7272 mL
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計算

In vivo Formulation Calculator (Clear solution) of N-acetyl-L-Carnosine

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 17 reference(s) in Google Scholar.)

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