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NH2-C6-ARC186 sodium

カタログ番号GC71259

NH2-C6-ARC186 sodiumは、他のペプチドや分子と結合することができるnh2-c6を有する変性arc186である。

Products are for research use only. Not for human use. We do not sell to patients.

NH2-C6-ARC186 sodium 化学構造

サイズ 価格 在庫数 個数
1mg
$166.00
在庫あり
5mg
$403.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description of NH2-C6-ARC186 sodium

NH2-C6-ARC186 sodium is a modified ARC186 with NH2-C6 that can be coupled to other peptides or molecules. ARC186 is a aptamer and a highly potent complement inhibitor that function by blocking the convertase-catalyzed activation of C5.

References:
[1]. Aptamer therapeutics useful in the treatment of complement-related disorders. WO2006088888A2.

Chemical Properties of NH2-C6-ARC186 sodium

Cas No. SDF
Formula M.Wt 12881
溶解度 H2O : 100 mg/mL (7.76 mM; Need ultrasonic) Storage -20°C, sealed storage, away from moisture
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of NH2-C6-ARC186 sodium

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.0776 mL 0.3882 mL 0.7763 mL
5 mM 0.0155 mL 0.0776 mL 0.1553 mL
10 mM 0.0078 mL 0.0388 mL 0.0776 mL
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**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

計算

In vivo Formulation Calculator (Clear solution) of NH2-C6-ARC186 sodium

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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