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PI3K/mTOR Inhibitor-2

カタログ番号GC19937

PI3K/mTOR Inhibitor-2 は、PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ の IC50 が 3.4/34/16/1 nM、mTOR の IC50 が 4.7 nM の強力なデュアル汎 PI3K/mTOR 阻害剤です。抗腫瘍活性。

Products are for research use only. Not for human use. We do not sell to patients.

PI3K/mTOR Inhibitor-2  化学構造

Cas No.: 1848242-58-9

サイズ 価格 在庫数 個数
10mM (in 1mL DMSO)
$248.00
在庫あり
5mg
$225.00
在庫あり
10mg
$351.00
在庫あり
50mg
$1,035.00
在庫あり
100mg
$1,446.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com

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  • GlpBio Citations

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Chemical Properties

Cas No. 1848242-58-9 SDF
Formula C20H13CIF2N4O4S M.Wt 478.86
溶解度 DMSO : 8.33 mg/mL (17.40 mM; Need ultrasonic) Storage Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.0883 mL 10.4415 mL 20.8829 mL
5 mM 0.4177 mL 2.0883 mL 4.1766 mL
10 mM 0.2088 mL 1.0441 mL 2.0883 mL
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計算

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

レビュー

Review for PI3K/mTOR Inhibitor-2

Average Rating: 5 ★★★★★ (Based on Reviews and 8 reference(s) in Google Scholar.)

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