Prostaglandin E2-1-glyceryl ester (Synonyms: PGE21glyceryl ester) |
| カタログ番号GC44718 |
2-アラキドノイルグリセロールは豚の脳から単離され、CB1受容体の自然なエンドカンナビノイドリガンドとして特徴付けられています。
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Cas No.: 37497-47-5
Sample solution is provided at 25 µL, 10mM.
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2-Arachidonoyl glycerol has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in prostaglandin glycerol ester formation. The biosynthesis of PGH, PGD, PGE, PGF, and Thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of these prostaglandin products has been investigated, little is known about their intrinsic biological activity.
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