Quisinostat dihydrochloride (Synonyms: JNJ-26481585 dihydrochloride) |
| カタログ番号GC19936 |
キジノスタット二塩酸塩 (JNJ-26481585 二塩酸塩) は、HDAC1、HDAC2、HDAC4、HDAC10、および HDAC11 に対してそれぞれ 0.11 nM、0.33 nM、0.64 nM、0.46 nM、および 0.37 nM の IC50 を有する経口投与可能な強力な汎 HDAC 阻害剤です。キジノスタット二塩酸塩は、広範囲の抗腫瘍活性を有します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 875320-31-3
Sample solution is provided at 25 µL, 10mM.
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Quisinostat dihydrochloride (JNJ-26481585 dihydrochloride) is an orally available, potent pan-HDAC inhibitor with IC50s of 0.11 nM, 0.33 nM, 0.64 nM, 0.46 nM, and 0.37 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11, respectively. Quisinostat dihydrochloride has a broad spectrum antitumoral activity[1].
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
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