(S)-Lansoprazole (Synonyms: (-)-Lansoprazole) |
カタログ番号GC41091 |
(S)-ランソプラゾールは、壁細胞内のH+/K+-刺激ATPaseポンプを不可逆的に阻害するプロトンポンプ阻害剤であり(IC50 = 5.2 μM)、胃酸分泌を抑制し、胃内pHを上昇させます。
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Cas No.: 138530-95-7
Sample solution is provided at 25 µL, 10mM.
(S)-Lansoprazole is a proton pump inhibitor that irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50 = 5.2 µM), inhibiting gastric acid secretion and increasing intragastric pH. It also inhibits acid formation in isolated canine parietal cells (IC50 = 82 µM). (S)-Lansoprazole is an enantiomerically pure form of lansoprazole . Both (S)- and (R)-lansoprazole are pharmacologically active with similar potencies.
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