Home>>JWH 073 N-(4-hydroxybutyl) β-D-Glucuronide

JWH 073 N-(4-hydroxybutyl) β-D-Glucuronide

Catalog No.GC43961

JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2.

Products are for research use only. Not for human use. We do not sell to patients.

JWH 073 N-(4-hydroxybutyl) β-D-Glucuronide Chemical Structure

Cas No.: 1322008-41-2

Size Price Stock Qty
500μg
$168.00
In stock
1mg
$318.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding CB1 and the peripheral CB2 receptor are 8.9 and 38 nM, respectively, for a CB1:CB2 ratio of 0.23. JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 N-(4-hydroxybutyl) β-D-Glucuronide is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018 . The physiological and toxicological properties of this compound have not been tested. This product is intended for forensic and research applications.

Chemical Properties

Cas No. 1322008-41-2 SDF
Canonical SMILES O=C(C1=CN(CCCCO[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O)C3=C1C=CC=C3)C4=C5C(C=CC=C5)=CC=C4
Formula C29H29NO8 M.Wt 519.6
Solubility DMSO: 10 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 1.9246 mL 9.6228 mL 19.2456 mL
5 mM 0.3849 mL 1.9246 mL 3.8491 mL
10 mM 0.1925 mL 0.9623 mL 1.9246 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 40 reference(s) in Google Scholar.)

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