1,2,3,4,5,6-Hexabromocyclohexane |
| Catalog No.GC17055 |
1,2,3,4,5,6-六溴环己烷（1,2,3,4,5,6-Hexabromocyclohexane）直接抑制JAK2激酶结构域内的口袋，抑制自身磷酸化。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1837-91-8
Sample solution is provided at 25 µL, 10mM.
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Potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation. A 16-hour treatment with 1 μM of compound reduces JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μM elimates nearly all JAK2 activity. Non-cytotoxic at 100 μM.
Review for 1,2,3,4,5,6-Hexabromocyclohexane
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for 1,2,3,4,5,6-Hexabromocyclohexane
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