>>Signaling Pathways>> Ox Stress Reagents>> Lipid Peroxidation>>10,13-epoxy-11-methyl-Octadecadienoic Acid

10,13-epoxy-11-methyl-Octadecadienoic Acid (Synonyms: F2 Furan Fatty Acid, 3-methyl-5-pentyl-2-Furannonanoic Acid, 9M5)

Catalog No.GC48782

A furan fatty acid

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10,13-epoxy-11-methyl-Octadecadienoic Acid Chemical Structure

Cas No.: 57818-39-0

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2.5mg
US$495.00
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Sample solution is provided at 25 µL, 10mM.

Description of 10,13-epoxy-11-methyl-Octadecadienoic Acid

10,13-epoxy-11-methyl-Octadecadienoic acid is a furan fatty acid.1,2,3,4,5 It prevents the formation of primary and secondary lipid oxidation products during the storage of ω-3 PUFA-enriched fish oil when used at concentrations of 50, 100, and 250 µM.1 10,13-epoxy-11-methyl-Octadecadienoic acid (20 µM) induces transcriptional activation of peroxisome proliferator-activated receptor γ (PPARγ) in a reporter assay.2 It increases lipid accumulation during the differentiation of 3T3-L1 preadipocytes to adipocytes when used at a concentration of 10 µM. 10,13-epoxy-11-methyl-Octadecadienoic acid has been found in marine bacteria, Adriatic fish, and butter.3,4,5

1.Buscato, M.H.H., MÜller, F., Vetter, W., et al.Furan fatty acids in enriched ω-3 fish oil: Oxidation kinetics with and without added monomethyl furan fatty acid as potential natural antioxidantFood Chem.327127087(2020) 2.Lauvai, J., Becker, A.-K., Lehnert, K., et al.The furan fatty acid 9M5 acts as a partial ligand to peroxisome proliferator-activated receptor gamma and enhances adipogenesis in 3T3-L1 preadipocytesLipids54277-288(2019) 3.Shirasaka, N., Nishi, K., and Shimizu, S.Occurrence of a furan fatty acid in marine bacteriaBiochimica et Biophysica Acta1258225-227(1995) 4.Pacetti, D., Alberti, F., Boselli, E., et al.Characterisation of furan fatty acids in Adriatic fishFood Chemistry122(1)209-215(2010) 5.Wendlinger, C., and Vetter, W.High concentrations of furan fatty acids in organic butter samples from the German marketJ. Agric. Food Chem.62(34)8740-8744(2014)

Chemical Properties of 10,13-epoxy-11-methyl-Octadecadienoic Acid

Cas No. 57818-39-0 SDF
Synonyms F2 Furan Fatty Acid, 3-methyl-5-pentyl-2-Furannonanoic Acid, 9M5
Canonical SMILES CCCCCC1=CC(C)=C(CCCCCCCCC(O)=O)O1
Formula C19H32O3 M.Wt 308.5
Solubility DMSO: slightly soluble,Methanol: slightly soluble Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 10,13-epoxy-11-methyl-Octadecadienoic Acid

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1 mg 5 mg 10 mg
1 mM 3.2415 mL 16.2075 mL 32.4149 mL
5 mM 0.6483 mL 3.2415 mL 6.483 mL
10 mM 0.3241 mL 1.6207 mL 3.2415 mL
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In vivo Formulation Calculator (Clear solution) of 10,13-epoxy-11-methyl-Octadecadienoic Acid

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 25 reference(s) in Google Scholar.)

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