(±)5-HETE lactone (Synonyms: (±)5-Hydroxyeicosatetraenoic Acid lactone) |
| Catalog No.GC40828 |
(±)5-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE.
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Cas No.: 73279-37-5
Sample solution is provided at 25 µL, 10mM.
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(±)5-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. (±)5-HETE lactone is an inhibitor of 5-lipoxygenase from rat basophilic leukemia cells with an IC50 of 27 µM. The lactone is several times more potent than the linear (±)5-HETE.
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