(±)-α-Tocopherol nicotinate |
| Catalog No.GC67191 |
(±)-α-토코페롤 니코티네이트, 비타민 E - 니코티네이트는 세포막에서 지질 과산화를 방지하는 경구 활성 지용성 항산화제입니다. 821d96072c2d58d8970e76f526b0f6b8(±)-α-토코페롤 니코티네이트는 혈액에서 α로 가수분해됩니다. 821d96072c2d58d8970e76f526b0f6b8- 토코페롤 및 니아신 관련 혈관 질환 연구에 사용될 수 있습니다.821d96072c2d58d8970e76f526b0f6b8
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 51898-34-1
Sample solution is provided at 25 µL, 10mM.
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(±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases[1][2].
(±)-α-Tocopherol nicotinate can help slow the progression of microangiopathy in type 2 diabetics by reducing lipid peroxidation stress in the red blood cell membrane, improving blood rheology and red blood cell deformability[1].
(±)-α-Tocopherol nicotinate (Vitamin E) (2 μg/mL, 24 h) increases the proportion of CD4+CD8-T cells in thymocytes by pretreating the thymic epithelial cell line IT45-R1 and then incubating it with immature T cells[2].
(±)-α-Tocopherol nicotinate (Vitamin E) (in animal feedings, 50 mg/kg or 585 mg/kg, 7 weeks) significantly increases the proportion of CD4+CD8- T cells and the expression of ICAM-1 in thymic epithelial cells (TECs) isolated of male Fisher rats at high dose concentrations of 585 mg/kg compared to low dose treatment of 50 mg/kg[2].
[1]. T W Chung, et al. Reducing lipid peroxidation stress of erythrocyte membrane by alpha-tocopherol nicotinate plays an important role in improving blood rheological properties in type 2 diabetic patients with retinopathy. Diabet Med. 1998 May;15(5):380-5.
[2]. Satoru Moriguchi, et al.Vitamin E enhances T cell differentiation through increased epithelial cell function in rat thymus,Nutrition Research,Volume 17, Issue 5,1997,Pages 873-883.
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