(±)-Cloprostenol sodium salt (Synonyms: (±)16mchlorophenoxy tetranor PGF2α, (±)16mchlorophenoxy tetranor Prostaglandin F2α, DLCloprostenol) |
| Catalog No.GC16838 |
(±)-클로프로스테놀 나트륨염(ICI 80996 나트륨염)은 강력한 합성 프로스타글란딘 유사체이며 황체 용해제로 작용하며 PGF2α 수용체 작용제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 55028-72-3
Sample solution is provided at 25 µL, 10mM.
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Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent[1], and is a PGF2α receptor agonist[2].
Cloprostenol is a PGF2α receptor agonist[2].Cloprostenol (0.1 μM) counteracts the adipogenic effects of statil, on both intracellular lipid accumulation and expression of transcripts for proadipogenic factors C/EBPα and PPARγ after treatment for 6 days[2].
Cloprostenol sodium salt (25 μg) decreases plasma progesterone in pregnant rats[1].
References:
[1]. Salazar H, et al. Luteolytic effects of a prostaglandin analogue, cloprostenol (ICI 80,996), in rats: ultrastructural and biochemical observations. Biol Reprod. 1976 May;14(4):458-72.
[2]. Pastel E, et al. Aldose reductases influence prostaglandin F2α levels and adipocyte differentiation in male mouse and human species. Endocrinology. 2015 May;156(5):1671-84.
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