>>Lipids>> P450>>19(S)-HETE

19(S)-HETE (Synonyms: 19(S)-Hydroxyeicosatetraenoic Acid)

Catalog No.GC40458

19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II.

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19(S)-HETE Chemical Structure

Cas No.: 115461-40-0

Size 가격 재고 수량
25μg
US$205.00
재고 있음
50μg
US$391.00
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100μg
US$740.00
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels. 19(S)-HETE stimulates both renal sodium-potassium ATPase and volume absorption in the rabbit proximal straight tubule.

Chemical Properties

Cas No. 115461-40-0 SDF
Synonyms 19(S)-Hydroxyeicosatetraenoic Acid
Canonical SMILES CC(O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O
Formula C20H32O3 M.Wt 320.5
Solubility DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 0.5 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 3.1201 mL 15.6006 mL 31.2012 mL
5 mM 0.624 mL 3.1201 mL 6.2402 mL
10 mM 0.312 mL 1.5601 mL 3.1201 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Review for 19(S)-HETE

Average Rating: 5 ★★★★★ (Based on Reviews and 26 reference(s) in Google Scholar.)

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