>>Signaling Pathways>> Microbiology & Virology>> HIV>>(1R)-Tenofovir amibufenamide

(1R)-Tenofovir amibufenamide (Synonyms: (1R)-HS-10234)

Catalog No.GC65363

(1R)-Tenofovir amibufenamide((1R)-HS-10234)는 Tenofovir amibufenamide의 이성질체이며 경구 활성 항바이러스제입니다.

Products are for research use only. Not for human use. We do not sell to patients.

(1R)-Tenofovir amibufenamide Chemical Structure

Cas No.: 1571076-15-7

Size 가격 재고 수량
5mg
US$405.00
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10mg
US$720.00
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고객 리뷰

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(1R)-Tenofovir amibufenamide ((1R)-HS-10234) is the isomer of Tenofovir amibufenamide, is an orally active antiviral agent. (1R)-Tenofovir amibufenamide ((1R)-HS-10234) is a HIV infection inhibitor and HBV infection inhibitor. (1R)-Tenofovir amibufenamide ((1R)-HS-10234) can be used for HIV infections, hepatitis B research[1].

[1]. Shahar N, et, al. Tenofovir prodrug and pharmaceutical uses thereof. WO2014032481.

Chemical Properties

Cas No. 1571076-15-7 SDF Download SDF
Synonyms (1R)-HS-10234
Formula C22H31N6O5P M.Wt 490.49
Solubility Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.0388 mL 10.1939 mL 20.3878 mL
5 mM 0.4078 mL 2.0388 mL 4.0776 mL
10 mM 0.2039 mL 1.0194 mL 2.0388 mL
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

리뷰

Review for (1R)-Tenofovir amibufenamide

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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