(1S,2S,3R)-DT-061 |
| Catalog No.GC34440 |
(1S,2S,3R)-DT-061은 DT-061의 거울상 이성질체입니다. DT-061은 단백질 포스파타제 2A(PP2A)의 경구 생체이용 활성화제이며 KRAS 돌연변이 및 MYC 유도 종양형성 치료에 적용될 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1809427-20-0
Sample solution is provided at 25 µL, 10mM.
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(1S,2S,3R)-DT-061 is an enantiomer of DT-061. DT-061 is an orally bioavailable activator of protein phosphatase 2A (PP2A) and could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis[1].
[1]. Kauko O, et al. PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Sci Transl Med. 2018 Jul 18;10(450). pii: eaaq1093.
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