>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>2-O-Methylcytosine

2-O-Methylcytosine

Catalog No.GC39527

DNA 부가물인 O-알킬화 유사체인 2-O-메틸시토신은 손상된 핵염기입니다.

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2-O-Methylcytosine Chemical Structure

Cas No.: 3289-47-2

Size 가격 재고 수량
100mg
US$46.00
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500mg
US$111.00
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고객 리뷰

Based on customer reviews.

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase[1].

[1]. Aliakbar Tehrani Z, et al. Comparison of gas phase intrinsic properties of cytosine and thymine nucleobases with their O-alkyl adducts: different hydrogen bonding preferences for thymine versus O-alkyl thymine. J Mol Model. 2013;19(8):2993‐3005.

Chemical Properties

Cas No. 3289-47-2 SDF
Canonical SMILES NC1=NC(OC)=NC=C1
Formula C5H7N3O M.Wt 125.13
Solubility DMSO: 60 mg/mL (479.50 mM) Storage 4°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 7.9917 mL 39.9584 mL 79.9169 mL
5 mM 1.5983 mL 7.9917 mL 15.9834 mL
10 mM 0.7992 mL 3.9958 mL 7.9917 mL
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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

리뷰

Review for 2-O-Methylcytosine

Average Rating: 5 ★★★★★ (Based on Reviews and 35 reference(s) in Google Scholar.)

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