(3-Carboxypropyl)trimethylammonium chloride |
| Catalog No.GC33797 |
(3-카르복시프로필)트리메틸암모늄 클로라이드는 식이성 붉은 고기의 카르니틴을 먹고 사는 장내 미생물총에 의해 중간 대사산물로 생성되는 혈관병성 물질입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6249-56-5
Sample solution is provided at 25 µL, 10mM.
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(3-Carboxypropyl)trimethylammonium chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat.
(3-Carboxypropyl)trimethylammonium chloride is produced as an intermediary metabolite by gut microbes of L-Carnitine to TMAO[1]. (3-Carboxypropyl)trimethylammonium chloride is implicated in arteriosclerosis and long-term cardiovascular death[2].
[1]. Koeth RA, et al. γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab. 2014 Nov 4;20(5):799-812. [2]. Susumu Ogawa, et al. The Dynamics of Carnitine, γ-butyrobetaine and Trimethylamine N-oxide in Diabetics and the Effects of Changes in Renal Function. Ogawa et al., J Nephrol Ren Dis 2017, 1:2
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