>>Signaling Pathways>> Others>>(6-)ε-​Aminocaproic acid

(6-)ε-​Aminocaproic acid (Synonyms: εAminocaproic Acid, EACA, NSC 26154, NSC 212532, NSC 400230)

Catalog No.GC15970

(6-)ε-아미노카프로산(EACA), 모노아미노 카르복실산은 플라스민과 플라스미노겐의 강력하고 경구 활성 억제제입니다.

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(6-)ε-​Aminocaproic acid Chemical Structure

Cas No.: 60-32-2

Size 가격 재고 수량
10mM (in 1mL Water)
US$39.00
재고 있음
50mg
US$35.00
재고 있음
100mg
US$56.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

6-Aminocaproic acid is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Target: Others6-aminohexanoic acid is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. Such enzymes include proteolytic enzymes like plasmin, the enzyme responsible for fibrinolysis. Aminocaproic acid is also an intermediate in the polymerization of Nylon-6, where it is formed by ring-opening hydrolysis of caprolactam.Aminocaproic acid is used to treat excessive postoperative bleeding, especially after procedures in which a great amount of bleeding is expected, such as cardiac surgery. Aminocaproic acid can also be used to treat the overdose and/or toxic effects of the thrombolytic pharmacologic agents tissue plasminogen activator and streptokinase [1, 2].

References:
[1]. Gardner, F.H. and R.E. Helmer, 3rd, Aminocaproic acid. Use in control of hemorrhage in patients with amegakaryocytic thrombocytopenia. JAMA, 1980. 243(1): p. 35-7.
[2]. Schwartz, B.S., et al., Epsilon-aminocaproic acid in the treatment of patients with acute promyelocytic leukemia and acquired alpha-2-plasmin inhibitor deficiency. Ann Intern Med, 1986. 105(6): p. 873-7.

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