>>Signaling Pathways>> Stem Cell>> GSK-3>>6-Me-ATP trisodium

6-Me-ATP trisodium

Catalog No.GC70708

6-Me-ATP trisodium은 n6개조 ATP 파생형이다.

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6-Me-ATP trisodium Chemical Structure

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59 mg(100 mM * 1 mL in Water)
US$261.00
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Sample solution is provided at 25 µL, 10mM.

Description of 6-Me-ATP trisodium

6-Me-ATP (N6-Methyl-ATP) trisodium is a N6-modified ATP derivative. 6-Me-ATP trisodium shows excellent binding affinity to GSK3, serving as the phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptide.

References:
[1]. Dong X, et al. Proteome-Wide Characterizations of N6-Methyl-Adenosine Triphosphate- and N6-Furfuryl-Adenosine Triphosphate-Binding Capabilities of Kinases. Anal Chem. 2021 Oct 5;93(39):13251-13259.

Chemical Properties of 6-Me-ATP trisodium

Cas No. SDF
Formula C11H15N5Na3O13P3 M.Wt 587.15
Solubility Storage Solution, -20°C, 2 years
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 6-Me-ATP trisodium

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.7031 mL 8.5157 mL 17.0314 mL
5 mM 0.3406 mL 1.7031 mL 3.4063 mL
10 mM 0.1703 mL 0.8516 mL 1.7031 mL
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In vivo Formulation Calculator (Clear solution) of 6-Me-ATP trisodium

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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