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α-Methyl-p-tyrosine

Catalog No.GC65892

α-메틸-p-티로신은 티로신을 레보도파(DOPA)로 전환시키는 효소 티로신 수산화효소의 경쟁적 억제제입니다. 821d96072c2d58d8970e76f526b0f6b8α-메틸-p-티로신은 티로신이 DOPA로 수산화되는 것을 억제하는 카테콜아민 합성의 경구 활성 억제제입니다.821d96072c2d58d8970e76f526b0f6b8

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α-Methyl-p-tyrosine Chemical Structure

Cas No.: 658-48-0

Size 가격 재고 수량
10mg
US$81.00
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

α-Methyl-p-tyrosine is a competitive inhibitor of the enzyme tyrosine hydroxylase, which converts tyrosine to Levodopa (DOPA). α-Methyl-p-tyrosine is an orally active inhibitor of catecholamine synthesis which inhibits the hydroxylation of tyrosine to DOPA[1].

Chemical Properties

Cas No. 658-48-0 SDF Download SDF
Formula C10H13NO3 M.Wt 195.22
Solubility Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 5.1224 mL 25.6121 mL 51.2243 mL
5 mM 1.0245 mL 5.1224 mL 10.2449 mL
10 mM 0.5122 mL 2.5612 mL 5.1224 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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