δ12-Prostaglandin J2 (Synonyms: Δ12PGJ2) |
| Catalog No.GC41109 |
δ12-Prostaglandin J2(δ12-PGJ2)는 다양한 종양 세포 성장에 항증식 효과가 있는 사이클로펜테논 프로스타글란딘(PG)입니다. δ12-프로스타글란딘 D2의 자연 발생 탈수 산물인 프로스타글란딘 J2는 카스파제 활성화를 통해 HeLa 세포에서 세포자멸사를 유도할 수 있습니다.
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Cas No.: 87893-54-7
Sample solution is provided at 25 µL, 10mM.
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δ12-PGJ2 is a decomposition product of PGD2 in aqueous media in the presence of albumin. It has antitumor and antiviral activity, inhibiting growth of cultured L1210 cells at with an IC50 value of 0.7 µg/ml. δ12-PGJ2 is present in normal human urine with a 24 hour excretion rate of 50-150 ng. It is also a moderately potent PPARγ ligand.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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