>>Signaling Pathways>> Chromatin/Epigenetics>> HIF>>AFP464

AFP464 (Synonyms: NSC710464 free base)

Catalog No.GC33416

AFP464(NSC710464 유리 염기)는 활성 HIF-1α입니다. IC50이 0.25 μ인 억제제; M은 또한 강력한 아릴 탄화수소 수용체(AhR) 활성화제입니다.

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AFP464 Chemical Structure

Cas No.: 468719-52-0

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

AFP464, is an active HIF-1α inhibitor with an IC50 of 0.25 μM, also is a potent aryl hydrocarbon receptor (AhR) activator.

[1]. Terzuoli E1, Aminoflavone, a ligand of the aryl hydrocarbon receptor, inhibits HIF-1alpha expression in an AhR-independent fashion. Cancer Res. 2010 Sep 1;70(17):6837-48.

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Average Rating: 5 ★★★★★ (Based on Reviews and 31 reference(s) in Google Scholar.)

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