>>Signaling Pathways>> TGF-β / Smad Signaling>> TGF-β Receptor>>ALK2-IN-2

ALK2-IN-2

Catalog No.GC65294

ALK2-IN-2는 IC50이 9nM이고 ALK3에 대해 700배 이상의 선택성을 갖는 액티빈 수용체 유사 키나제 2(ALK2)의 강력하고 선택적인 억제제입니다.

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ALK2-IN-2 Chemical Structure

Cas No.: 2254409-25-9

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$344.90
재고 있음
5mg
US$315.00
재고 있음
10mg
US$495.00
재고 있음
25mg
US$891.00
재고 있음
50mg
US$1,485.00
재고 있음
100mg
US$2,025.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700-fold selectivity against ALK3[1].

[1]. Jiang JK, et al. Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3356-3362.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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