ALK2-IN-2 |
Catalog No.GC65294 |
ALK2-IN-2는 IC50이 9nM이고 ALK3에 대해 700배 이상의 선택성을 갖는 액티빈 수용체 유사 키나제 2(ALK2)의 강력하고 선택적인 억제제입니다.
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Cas No.: 2254409-25-9
Sample solution is provided at 25 µL, 10mM.
ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700-fold selectivity against ALK3[1].
[1]. Jiang JK, et al. Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3356-3362.
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