>>Signaling Pathways>> Apoptosis>> Other Apoptosis>>(+)-ar-Turmerone

(+)-ar-Turmerone (Synonyms: (S)(+)arTurmerone)

Catalog No.GC45256

(+)-ar-Turmerone((+)-(+)-ar-Turmerone)은 항종양 및 항염증 활성이 있는 Curcuma longa 허브의 주요 생리 활성 화합물입니다.

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(+)-ar-Turmerone Chemical Structure

Cas No.: 532-65-0

Size 가격 재고 수량
1mg
US$83.00
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5mg
US$378.00
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10mg
US$672.00
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-turmerone ((+)-ar-Turmerone) activates apoptotic protein in human lymphoma U937 cells[3]. ar-Turmerone ((+)-ar-Turmerone) exerts positive modulation on murine DCs, induces NSC proliferation and constitutes a promising therapeutic agent for various neurologic disorders[4][5].

References:
[1]. Liju VB, et al. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L. Indian J Pharmacol. 2011 Sep;43(5):526-31.
[2]. Yue GG, et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2011-20.
[3]. Lee Y, et al. Activation of apoptotic protein in U937 cells by a component of turmeric oil. BMB Rep. 2009 Feb 28;42(2):96-100.
[4]. Yonggang T, et al. Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR). Hum Vaccin Immunother. 2012 Oct;8(10):1416-24.
[5]. Hucklenbroich J, et al. Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo. Stem Cell Res Ther. 2014 Sep 26;5(4):100.

Chemical Properties

Cas No. 532-65-0 SDF
Synonyms (S)(+)arTurmerone
Canonical SMILES CC1=CC=C([C@@H](C)CC(/C=C(C)/C)=O)C=C1
Formula C15H20O M.Wt 216.3
Solubility Ethanol: Miscible Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 4.6232 mL 23.116 mL 46.2321 mL
5 mM 0.9246 mL 4.6232 mL 9.2464 mL
10 mM 0.4623 mL 2.3116 mL 4.6232 mL
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