C18:1 Ceramide (d18:1/18:1(9Z)) (Synonyms: Cer(d18:1/18:1(9Z))) |
| Catalog No.GC43055 |
C18:1 Ceramide is a naturally occurring ceramide.
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Cas No.: 5966-28-9
Sample solution is provided at 25 µL, 10mM.
C18:1 Ceramide is a naturally occurring ceramide.[1][2][3] Levels of C18:1 ceramide are elevated in overweight and insulin-resistant mice and cattle.[1][2] C18:1 Ceramide is also increased in the plasma and ovarian tissue of patients with advanced ovarian cancer. [3]
Reference:
[1]. Sajan, M.P., Ivey, R.A., Lee, M.C., et al. Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation. J. Lipid Res. 56(1), 70-80 (2015).
[2]. Rico, J.E., Bandaru, V.V., Dorskind, J.M., et al. Plasma ceramides are elevated in overweight Holstein dairy cows experiencing greater lipolysis and insulin resistance during the transition from late pregnancy to early lactation. J. Dairy Sci. 98(11), 7757-7770 (2015).
[3]. Knapp, P., Bodnar, L., Błachnio-Zabielska, A., et al. Plasma and ovarian tissue sphingolipids profiling in patients with advanced ovarian cancer. Gynecol. Oncol. 147(1), 139-144 (2017).
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