>>Lipids>> Sphingolipids>>C6 NBD Ceramide (d18:1/6:0)

C6 NBD Ceramide (d18:1/6:0) (Synonyms: C6 NBD Ceramide, NBD Cer(18:1/2:0), NBD Ceramide (d18:1/6:0) , N-C6-NBD-D-erythro-Sphingosine)

Catalog No.GC43096

C6 NBD Ceramide(d18:1/6:0)는 세포막 투과성을 가진 골지체 형광 프로브입니다.

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C6 NBD Ceramide (d18:1/6:0) Chemical Structure

Cas No.: 94885-02-6

Size 가격 재고 수량
1mg
US$248.00
재고 있음
5mg
US$1,119.00
재고 있음
10mg
US$1,987.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

C6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-permeable ceramides.1 It is as effective as C6 ceramide in the inhibition of viral glycoprotein transport through the Golgi.[1] C6 NBD ceramide has been used as a fluorescent substrate for the activity of UDP-glucose:ceramide glucosyltransferase and to demonstrate the translocation of glucocerebroside and sphingomyelin from the Golgi to the plasma membrane.[2],[3]

Reference:
[1]. Rosenwald, A.G., and Pagano, R.E. Inhibition of glycoprotein traffic through the secretory pathway by ceramide. J. Biol. Chem. 268(7), 4577-4579 (1993).
[2]. Paul, P., Kamisaka, Y., Marks, D.L., et al. Purification and characterization of UDP-glucose: Ceramide glucosyltransferase from rat liver Golgi membranes. J. Biol. Chem. 271(4), 2287-2293 (1996).
[3]. Lipsky, N.G., and Pagano, R.E. Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: Endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the golgi apparatus en route to the plasma membrane. J. Cell. Biol. 100(1), 27-34 (1985).

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