>>Signaling Pathways>> Neuroscience>> Behavioral Neuroscience>>3-Amino-2,6-Piperidinedione

3-Amino-2,6-Piperidinedione (Synonyms: α-Aminoglutarimide, 3-Aminoglutarimide, Glutamimide)

Catalog No.GC46583

An active metabolite of (±)-thalidomide

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3-Amino-2,6-Piperidinedione Chemical Structure

Cas No.: 2353-44-8

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50 mg
US$60.00
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100 mg
US$108.00
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250 mg
US$240.00
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500 mg
US$419.00
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

3-Amino-2,6-piperidinedione is an active metabolite of (±)-thalidomide .1 In vivo, 3-amino-2,6-piperidinedione (400 mg/kg) increases hexobarbitone-induced sleeping time in rats.

1.Fabro, S., Schumacher, H., Smith, R.L., et al.The metabolism of thalidomide: Some biological effects of thalidomide and its metabolitesBr. J. Pharmacol. Chemother.25(2)352-362(1965)

Chemical Properties

Cas No. 2353-44-8 SDF
Synonyms α-Aminoglutarimide, 3-Aminoglutarimide, Glutamimide
Canonical SMILES O=C1C(CCC(N1)=O)N
Formula C5H8N2O2 M.Wt 128.1
Solubility PBS (pH 7.2): 10 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 7.8064 mL 39.032 mL 78.064 mL
5 mM 1.5613 mL 7.8064 mL 15.6128 mL
10 mM 0.7806 mL 3.9032 mL 7.8064 mL
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Review for 3-Amino-2,6-Piperidinedione

Average Rating: 5 ★★★★★ (Based on Reviews and 11 reference(s) in Google Scholar.)

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