ε-Rhodomycinone (Synonyms: NSC 196524) |
| Catalog No.GC48532 |
A bacterial metabolite and precursor to rhodomycin D
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 21288-60-8
Sample solution is provided at 25 µL, 10mM.
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ε-Rhodomycinone is a bacterial metabolite that has been found in S. griseoruber.1 It is a precursor to rhodomycin D, which is an intermediate in the bioconversion of ε-rhodomycinone to daunorubicin and doxorubicin .2,3
1.Podojil, M., BlumauerovÁ, M., P?ikrylovÁ, V., et al.Production of rhodomycins in Streptomyces griseoruber 4620Folia Microbiol. (Praha)25(6)464-466(1980) 2.Olano, C., Lomovskaya, N., Fonstein, L., et al.A two-plasmid system for the glycosylation of polyketide antibiotics: Bioconversion of ε-rhodomycinone to rhodomycin DChem. Biol.6(12)845-855(1999) 3.Dickens, M.L., Priestley, N.D., and Strohl, W.R.In vivo and in vitro bioconversion of ε-rhodomycinone glycoside to doxorubicin: Functions of DauP, DauK, and DoxAJ. Bacteriol.179(8)2641-2650(1997)
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