(S)-O-Desmethyl Naproxen (Synonyms: (S)-6-Desmethyl Naproxen) |
| Catalog No.GC49179 |
A metabolite of (S)-naproxen
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Cas No.: 52079-10-4
Sample solution is provided at 25 µL, 10mM.
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(S)-O-Desmethyl naproxen is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+)-naproxen ((S)-naproxen; It is formed from (S)-naproxen by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9.
1.Miners, J.O., Soulter, S., Tukey, R.H., et al.Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxenBiochem. Pharmacol.51(8)1003-1008(1996)
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