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(+)-Coclaurine hydrochloride (Synonyms: (+)-(R)-Coclaurine hydrochloride; (R)-Coclaurine hydrochloride; d-Coclaurine hydrochloride)

Catalog No.GC63999

(+)-Coclaurine ((+)-(R)-Coclaurine) 염산염, 다양한 식물 공급원에서 분리된 benzyltetrahydroisoquinoline 알칼로이드.

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(+)-Coclaurine hydrochloride Chemical Structure

Cas No.: 19894-19-0

Size 가격 재고 수량
1 mg
US$252.00
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5 mg
US$882.00
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10 mg
US$1,350.00
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride, benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine hydrochloride has anti-aging activity[1][2].

An intracerebroventricular injection of (+)-Coclaurine (d-Coclaurine; 50 μg) hydrochloride produces a slight increase in 3,4-dihydroxyphenylacetic acid level and a significant increase in homovanillic acid level in the mouse striatum. (+)-Coclaurine hydrochloride blocks postsynaptic but not presynaptic dopamine receptors in the mouse striatum[2].

[1]. [1]Siva S Panda, et al. Protective effects of Aporosa octandra bark extract against D-galactose induced cognitive impairment and oxidative stress in mice. Heliyon. 2018 Nov 30;4(11):e00951.
[2]. H Watanabe, et al. Effects of d-coclaurine and d-reticuline, benzyltetrahydroisoquinoline alkaloids, on levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid in the mouse striatum. J Pharmacobiodyn. 1983 Oct;6(10):793-6.

Chemical Properties

Cas No. 19894-19-0 SDF Download SDF
Synonyms (+)-(R)-Coclaurine hydrochloride; (R)-Coclaurine hydrochloride; d-Coclaurine hydrochloride
Formula C17H20ClNO3 M.Wt 321.8
Solubility Storage 4°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 3.1075 mL 15.5376 mL 31.0752 mL
5 mM 0.6215 mL 3.1075 mL 6.215 mL
10 mM 0.3108 mL 1.5538 mL 3.1075 mL
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Average Rating: 5 ★★★★★ (Based on Reviews and 39 reference(s) in Google Scholar.)

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