>>Signaling Pathways>> Tyrosine Kinase>> Bcr-Abl>>CZC-8004 (CZC-00008004)

CZC-8004 (CZC-00008004) (Synonyms: Dianilinopyrimidine-01)

Catalog No.GC33351

아미노피리미딘인 CZC-8004(CZC-00008004)(CZC-00008004)는 범 키나제 억제제입니다. CZC-8004(CZC-00008004)는 각각 650 및 437 nM의 IC50 값으로 EGFR 및 VEGFR2를 비롯한 다양한 티로신 키나제에 결합할 수 있습니다.

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CZC-8004 (CZC-00008004) Chemical Structure

Cas No.: 916603-07-1

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$132.00
재고 있음
5mg
US$119.00
재고 있음
10mg
US$211.00
재고 있음
25mg
US$450.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase.

[1]. CZC-8004 is a pan-kinase inhibitor, with low micromolar IC50 values for tyrosine kinase. [2]. Bantscheff M, et al. Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nat Biotechnol. 2007 Sep;25(9):1035-44.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 29 reference(s) in Google Scholar.)

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